Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708713 | 0.93 | PPARG (0.51) | PPARG | |
| SCHEMBL2786646 | 0.93 | PPARG (0.67) | PPARG | |
| SCHEMBL2787967 | 0.93 | PPARG (0.67) | PPARG | |
| SCHEMBL7923239 | 0.84 | PPARG (0.56) | PPARG | |
| SCHEMBL7922605 | 0.84 | PPARG (0.56) | PPARG | |
| SCHEMBL27532922 | 0.83 | PPARG (0.53) | PPARG | |
| SCHEMBL2785014 | 0.81 | PPARG (0.88) | PPARG | |
| SCHEMBL8457042 | 0.76 | PPARG (0.51) | PPARG | |
| SCHEMBL2786755 | 0.75 | PPARG (0.81) | PPARG | |
| SCHEMBL2786213 | 0.74 | PPARG (1.00) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3255930-B2 | — | — | 2002-02-12 | — | — | JP | claimed |
| JP-2000507216-A | — | — | 2000-06-13 | — | — | JP | claimed |
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | claimed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | claimed |