Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | KLK3 | P07288 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 5/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431382 | 0.87 | NPC1 (0.52) | ADORA2AKDM4EMEN1KMT2ADCTPP1 | |
| SCHEMBL7709217 | 0.86 | GRM5 (0.50) | ADORA2AKLK3KDM4EDCTPP1ATM | |
| SCHEMBL7483006 | 0.85 | NPC1 (0.53) | ADORA2AKDM4EMEN1KMT2ADCTPP1 | |
| SCHEMBL7708845 | 0.83 | ADORA2A (0.54) | ADORA2AKDM4EMEN1KMT2ADCTPP1 | |
| SCHEMBL7428533 | 0.82 | ADORA2A (0.60) | ADORA2AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL7703002 | 0.82 | ADORA2A (0.47) | ADORA2AKDM4EMEN1KMT2AATM | |
| SCHEMBL7481790 | 0.81 | ADORA2A (0.52) | ADORA2AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL7709146 | 0.81 | ADORA2A (0.52) | ADORA2AKDM4EMEN1KMT2ADCTPP1 | |
| SCHEMBL7708907 | 0.81 | ADORA2A (0.52) | ADORA2AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL7427435 | 0.81 | ADORA2A (0.54) | ADORA2AKDM4EMEN1KMT2ADCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |