Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 1.00 |
| ▸ | MEN1 | O00255 | 13/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 9/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.65 |
| ▸ | CCR6 | P51684 | 3/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.65 |
| ▸ | XBP1 | P17861 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.58 |
| ▸ | FEN1 | P39748 | 2/20 | 0.58 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618712 | 0.84 | MEN1 (0.73) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL7709662 | 0.82 | KMT2A (0.69) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL14257646 | 0.82 | MEN1 (0.69) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL10261656 | 0.81 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL29903439 | 0.81 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| Ammonia Solution, Strong SCHEMBL6416651 | 0.81 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL10018568 | 0.81 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL13495357 | 0.81 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL16213360 | 0.81 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5116137 | 0.80 | MEN1 (0.67) | KMT2AMEN1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | claimed |
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |