Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 7/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709692 | 0.86 | TYMS (0.51) | TYMSALOX15TDP1DHFR | |
| SCHEMBL29836499 | 0.80 | TYMS (0.49) | TYMSALOX15TDP1 | |
| SCHEMBL4959190 | 0.77 | TYMS (0.61) | TYMSALOX15TDP1DHFRAHR | |
| SCHEMBL7709648 | 0.76 | TYMS (0.45) | TYMSALOX15TDP1 | |
| SCHEMBL7703859 | 0.73 | TYMS (0.49) | TYMSALOX15TDP1DHFR | |
| SCHEMBL30608351 | 0.73 | TYMS (0.61) | TYMSALOX15TDP1 | |
| SCHEMBL4533766 | 0.73 | TYMS (0.61) | TYMSALOX15TDP1 | |
| SCHEMBL10267341 | 0.72 | TYMS (0.70) | TYMSALOX15TDP1 | |
| SCHEMBL6719946 | 0.72 | TYMS (0.55) | TYMSALOX15TDP1 | |
| SCHEMBL9078978 | 0.71 | TYMS (0.46) | TYMSALOX15TDP1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |