SCHEMBL7709604

SCHEMBL7709604

O=C(O)/C=C/C(=O)OC1([SiH3])CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10537003 0.93
SCHEMBL10887049 0.86
SCHEMBL381790 0.80
SCHEMBL28119781 0.79
SCHEMBL6918832 0.79 KMT2A (0.42) HCAR2
SCHEMBL27987466 0.78
SCHEMBL2130742 0.77
SCHEMBL3116445 0.75
SCHEMBL21874761 0.74
SCHEMBL27502221 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1080138-B1 PLASMA SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES BAUSCH & LOMB (US) 2002-08-28 EP disclosed
EP-1080139-A1 PLASMA SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 2001-03-07 EP disclosed
EP-1080138-A1 PLASMA SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 2001-03-07 EP disclosed
US-6193369-B1 Plasma surface treatment of silicone hydrogel contact lenses BAUSCH & LOMB INCORPORATED 2001-02-27 US disclosed
WO-1999057177-A1 PLASMA SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1999-11-11 WO disclosed
WO-1999057178-A1 PLASMA SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1999-11-11 WO disclosed