Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710133 | 1.00 | F10 (0.50) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7707088 | 0.90 | F10 (0.53) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7707085 | 0.90 | F10 (0.53) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7710193 | 0.89 | F10 (0.48) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7710190 | 0.89 | F10 (0.48) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7709912 | 0.89 | F10 (0.48) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7709911 | 0.89 | F10 (0.48) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL6620052 | 0.89 | F10 (0.52) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7710430 | 0.89 | F10 (0.52) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7709871 | 0.88 | F10 (0.53) | F10ITGB3ITGA2BPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | claimed |