Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.63 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.63 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885601 | 0.95 | MAPK10 (0.69) | MAPK10MAPK9MAPK8CCNT1CCNA2 | |
| SCHEMBL2884761 | 0.90 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL2883033 | 0.86 | MAPK10 (0.72) | MAPK10MAPK9MAPK8CCNT1CCNA2 | |
| SCHEMBL2878978 | 0.84 | MAPK10 (0.71) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL2879038 | 0.83 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL4022971 | 0.83 | MAPK10 (0.84) | MAPK10MAPK9MAPK8CCNT1CCNA2 | |
| SCHEMBL4023159 | 0.82 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL2886187 | 0.82 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL2881373 | 0.82 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL4026673 | 0.82 | MAPK10 (0.75) | MAPK10MAPK9MAPK8CCNT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |