Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581468 | 0.77 | PDE10A (1.00) | PDE10AKMT2ATSHRDHODHLMNA | |
| Hydrochloric Acid SCHEMBL27511204 | 0.76 | PDE10A (0.97) | PDE10AKMT2ATSHRDHODHLMNA | |
| SCHEMBL2956896 | 0.75 | MAPT (0.64) | PDE10AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL27710092 | 0.73 | PDE10A (0.49) | PDE10AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL17175790 | 0.73 | PDE10A (0.62) | PDE10AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13957825 | 0.72 | PDE10A (1.00) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL1902587 | 0.71 | MEN1 (1.00) | PDE10AKMT2AMEN1MAPTALDH1A1 | |
| Methylene Chloride SCHEMBL30760638 | 0.71 | MAPT (0.58) | PDE10AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL14106730 | 0.70 | PDE10A (0.72) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL7715419 | 0.70 | KDM4E (0.81) | PDE10AKMT2ADHODHMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376670-B1 | BACTERICIDE FOR GRAMPOSITIVE BACTERIA | SEPRACOR INC. | 2002-04-23 | — | — | US | disclosed |
| US-6207679-B1 | FOR INHIBITING GROWTH OF BACTERIAL MICROORGANISMS | SEPRACOR, INC. | 2001-03-27 | — | — | US | disclosed |
| US-6172084-B1 | BACTERICIDES AGAINST ANTIBIOTIC RESISTANT STRAINS OF STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS | SEPRACOR, INC. | 2001-01-09 | — | — | US | disclosed |
| US-6103905-A | EFFECTIVE AGAINST DRUG RESISTANT GRAMPOSITIVE BACTERIAL INFECTIONS; ANTIBIOTICS | SEPRACOR, INC. (US) | 2000-08-15 | — | — | US | disclosed |
| WO-2000034265-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS | SEPRACOR, INC. (US) | 2000-06-15 | — | — | WO | disclosed |
| EP-0991623-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS, USES AND COMPOSITIONS RELATED THERETO | SEPRACOR, INC. (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057931-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS, USES AND COMPOSITIONS RELATED THERETO | SEPRACOR INC. (US) | 1998-12-23 | — | — | WO | disclosed |