SCHEMBL7710667

SCHEMBL7710667

CCCCCCCCC=CCCCCCCCCOc1ccccc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
LMNA P02545 2/20 0.63
NR1I2 O75469 1/20 0.63
CHRM2 P08172 1/20 0.63
CYP3A4 P08684 1/20 0.63
ADRA2A P08913 1/20 0.63
MAPT P10636 1/20 0.63
OPRK1 P41145 1/20 0.63
HTR2B P41595 1/20 0.63
SLC6A3 Q01959 1/20 0.63
HDAC6 Q9UBN7 1/20 0.63
PTPN11 Q06124 6/20 0.60
ALDH1A1 P00352 3/20 0.55
PTK2B Q14289 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
PTPN1 P18031 3/20 0.53
KDM4E B2RXH2 1/20 0.52
RECQL P46063 1/20 0.52
S1PR3 Q99500 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6084916 1.00 KMT2A (0.63) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL28977382 1.00 KMT2A (0.63) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL27864903 1.00 KMT2A (0.63) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL6084911 1.00 KMT2A (0.63) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL7710661 1.00 KMT2A (0.63) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL2887745 0.97 KMT2A (0.59) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL6925754 0.97 KMT2A (0.59) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL168816 0.91 KMT2A (0.74) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL3665313 0.91 KMT2A (0.74) KMT2AMEN1LMNANR1I2CHRM2
SCHEMBL527254 0.91 KMT2A (0.74) KMT2AMEN1LMNANR1I2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0977725-A1 NEW FATTY ACID DERIVATIVES NORSK HYDRO ASA (NO) 2000-02-09 EP claimed
WO-1998032718-A1 NEW FATTY ACID DERIVATIVES NORSK HYDRO ASA (NO) 1998-07-30 WO claimed
US-6368615-B1 POLYMER OF UNSATURATED ESTER OF SALICYLIC ACID GUTTAG ALVIN (US) 2002-04-09 US disclosed
US-6037338-A AND REDUCING RISK OF HEART ATTACKS GUTTAG ALVIN (US) 2000-03-14 US disclosed
US-5910511-A ALTERNATIVE TO ASPIRIN WHICH HAS LESSER UNDESIRABLE SIDE EFFECTS GUTTAG ALVIN (US) 1999-06-08 US disclosed
US-5760261-A ANTINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECTREDUCTION GUTTAG ALVIN (US) 1998-06-02 US disclosed