Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168948 | 0.79 | — | — | |
| SCHEMBL135371 | 0.75 | POLB (0.32) | — | |
| SCHEMBL4870509 | 0.75 | — | — | |
| SCHEMBL2901795 | 0.75 | — | — | |
| SCHEMBL336316 | 0.73 | — | — | |
| SCHEMBL9503754 | 0.73 | — | — | |
| SCHEMBL29039601 | 0.72 | — | — | |
| SCHEMBL17641593 | 0.71 | — | — | |
| SCHEMBL30871009 | 0.71 | — | — | |
| SCHEMBL3354022 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259779-B1 | 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds | AMERICAN CYANAMID CO (US) | 1994-08-10 | — | — | EP | claimed |
| US-6362168-B1 | Antiparasitic agents | PFIZER INC. | 2002-03-26 | — | — | US | disclosed |
| US-6103504-A | STREPTOMYCES MUTANT LACKING BRANCHED-CHAIN AMINO ACID TRANSAMINASE ACTIVITY, BRANCHED-CHAIN OXO ACID BIOSYNTHETIC ACTIVITY AND LACKING AVERMECTIN B-O-METHYL TRANSFERASE ACTIVITY; FOR PRODUCTION OF PARASITIDES AND ANTHELMINTICS | PFIZER INC. (US) | 2000-08-15 | — | — | US | disclosed |
| US-5840704-A | INSECTICIDES, MITICIDES, ANTHELMINTICS | PFIZER INC. (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0640142-B1 | PROCESS FOR PRODUCTION OF AVERMECTINS AND CULTURES THEREFOR | PFIZER (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5702924-A | Process for preparing antiparasitic agents | PFIZER INC. (US) | 1997-12-30 | — | — | US | disclosed |
| US-5583015-A | CULTURING MUTANT STRAIN OF STREPTOMYCES AVERMITILIS LACKING BRANCHED CHAIN AMINO ACID TRANSAMINASE AND/OR 2-OXO ACID DEHYDROGENASE ACTIVITY UNDER AEROBIC CONDITIONS IN AQUEOUS NUTRIENT MEDIUM CONTAINING SPECIFIED ACID OR PRECURSOR | PFIZER INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5583029-A | PARASITICIDES | PFIZER INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5576199-A | CULTURE OF STREPTOMYCES UNDER AEROBIC CONDITIONS IN NUTRIENTS | PFIZER INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5576200-A | CULTURING A MUTANT STRAIN OF STREPTOMYCES | PFIZER INC. (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0237339-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| EP-0214731-A2 | Antiparasitic avermectin and milbemycin derivatives and process for their preparation | Pfizer Limited (GB) | 1987-03-18 | — | — | EP | disclosed |
| EP-0100900-B1 | NOVEL (3.2.0.) BICYCLOHEPTANONE OXIME ETHERS WITH VALUABLE THERAPEUTIC PROPERTIES | SYNTEX (U.S.A.) INC. (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4552898-A | CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-11-12 | — | — | US | disclosed |
| US-4550160-A | Processes for the interconversion of C-076 compounds | MERCK & CO., INC. (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0040913-B1 | 23-KETO DERIVATIVES OF C-076 COMPOUNDS, THEIR PREPARATION AND ANTI-PARASITIC USE | MERCK & CO. INC. (US) | 1984-07-25 | — | — | EP | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4328335-A | PARASITICIDES, CULTURE PRODUCT OF STREPTOMYCES REACTED WITH A THIOCARBONYL HALIDE | MERCK & CO., INC. (US) | 1982-05-04 | — | — | US | disclosed |
| EP-0040913-A1 | 23-Keto derivatives of C-076 compounds, their preparation and anti-parasitic use | MERCK & CO. INC. (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4289760-A | ANTHELMINTICS, PARASITICIDES | MERCK & CO., INC. (US) | 1981-09-15 | — | — | US | disclosed |