Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.65 |
| ▸ | CTSD | P07339 | 10/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711604 | 0.89 | BACE1 (0.67) | BACE1CTSDBACE2 | |
| SCHEMBL2574130 | 0.88 | BACE1 (0.66) | BACE1CTSDBACE2 | |
| SCHEMBL7712107 | 0.87 | BACE1 (0.77) | BACE1CTSDBACE2 | |
| SCHEMBL2573986 | 0.87 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL7713684 | 0.87 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL2577771 | 0.86 | BACE1 (0.67) | BACE1CTSDBACE2CTSB | |
| SCHEMBL2574619 | 0.85 | BACE1 (0.66) | BACE1CTSDBACE2 | |
| SCHEMBL2573768 | 0.85 | BACE1 (0.54) | BACE1CTSDCTSB | |
| SCHEMBL2575427 | 0.84 | BACE1 (0.69) | BACE1CTSDBACE2CTSB | |
| SCHEMBL2572115 | 0.84 | BACE1 (0.73) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |