SCHEMBL7712502

SCHEMBL7712502

CCCCCCCCCCCCCCCCc1c(C(=O)O)ccc(NC(=O)CC(=O)C(C)(C)C)c1OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 12/20 0.38
PLK3 Q9H4B4 5/20 0.38
PPARA Q07869 2/20 0.36
PPARG P37231 1/20 0.36
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
POLB P06746 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RARB P10826 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7712497 0.84 HSP90AA1 (0.39) PLK1PLK3PPARAPPARGKDM4E
SCHEMBL7706061 0.77 KDM4E (0.33) HPGDKDM4EALDH1A1
SCHEMBL7709910 0.76 PPARA (0.43) PLK1PLK3PPARAPPARGPOLB
SCHEMBL7712340 0.74 PPARA (0.40) PLK1PLK3PPARAPPARGHPGD
SCHEMBL7712500 0.69 NPC1 (0.38) PPARAPPARGALDH1A1
SCHEMBL14836066 0.69 PPARA (0.60) PLK1PLK3PPARAPPARGALDH1A1
SCHEMBL93465 0.69 PPARA (0.60) PLK1PLK3PPARAPPARGALDH1A1
SCHEMBL14836443 0.69 PPARA (0.60) PLK1PLK3PPARAPPARGALDH1A1
SCHEMBL6864045 0.69 PPARA (0.60) PLK1PLK3PPARAPPARGALDH1A1
SCHEMBL17995610 0.69 PPARA (0.60) PLK1PLK3PPARAPPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1217435-A1 Silver halide photographic element and imaging process EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
US-6361931-B1 REACTIVITY, STABILITY EASTMAN KODAK COMPANY 2002-03-26 US disclosed