SCHEMBL7713612

SCHEMBL7713612

NNc1c(Cl)c(Cl)cc(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.47
HPGD P15428 6/20 0.41
HSD17B10 Q99714 6/20 0.41
TSHR P16473 6/20 0.41
CASP1 P29466 1/20 0.41
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 3/20 0.38
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
AHR P35869 4/20 0.35
RAPGEF4 Q8WZA2 1/20 0.32
HSP90AA1 P07900 2/20 0.32
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL20984770 0.97 CYP3A4 (0.45) CYP3A4HPGDHSD17B10TSHRCASP1
Hydrochloric Acid SCHEMBL20984883 0.97 CYP3A4 (0.45) CYP3A4HPGDHSD17B10TSHRCASP1
Oxalic Acid SCHEMBL20984222 0.86 MAPT (0.40) CYP3A4HPGDHSD17B10TSHRCASP1
Phosphoric Acid SCHEMBL20984304 0.86 HPGD (0.37) CYP3A4HPGDHSD17B10TSHRCASP1
Sulfuric Acid SCHEMBL20984654 0.86 HPGD (0.39) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL10620119 0.83 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRCASP1
Nitric Acid SCHEMBL20984327 0.82 TSHR (0.47) CYP3A4HPGDHSD17B10TSHRCASP1
Bromide SCHEMBL20984765 0.81 CYP3A4 (0.48) CYP3A4HPGDHSD17B10TSHRCASP1
Hydrochloric Acid SCHEMBL20984596 0.81 CYP3A4 (0.48) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL9337623 0.74 KDM4E (0.41) GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108101762-A 2,3,5,6- tetrachloroquinones and preparation method thereof 夏月宏 2018-06-01 CN claimed
US-5001262-A Method for synthesizing an aromatic hydrazine compound EASTMAN KODAK COMPANY (US) 1991-03-19 US claimed
CN-109824679-A A kind of preparation method of substituted aryl porphyrin 中国科学院长春应用化学研究所 2019-05-31 CN disclosed
CN-108101762-A 2,3,5,6- tetrachloroquinones and preparation method thereof 夏月宏 2018-06-01 CN disclosed
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
US-6372774-B1 THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES RHONE-POULENC AGRICULTURE LTD. (GB) 2002-04-16 US disclosed
US-5916618-A PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT RHONE-POULENC AGRICULTURE LTD. (GB) 1999-06-29 US disclosed
US-5714191-A PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT RHONE-POULENC AGRICULTURE LTD. (GB) 1998-02-03 US disclosed
US-5608077-A INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS RHONE-POULENC AGRICULTURE LTD. (GB) 1997-03-04 US disclosed
US-5547974-A INSECTICIDES, NEMATOCIDES, ANTHELMINTICS RHONE-POULENC AGRICULTURE LTD. (GB) 1996-08-20 US disclosed
CN-1025811-C Pesticidal method using N-phenyl pyrazoles MAY & BAKER LTD (GB) 1994-09-07 CN disclosed
EP-0234119-B1 Pesticidal method using N-phenylpyrazoles RHONE POULENC AGROCHIMIE (FR) 1994-08-24 EP disclosed
EP-0353931-B1 Method of making aromatic hydrazines EASTMAN KODAK CO (US) 1994-06-08 EP disclosed
EP-0579280-A1 Pesticidal method using N-phenylpyrazoles RHONE-POULENC AGROCHIMIE (FR) 1994-01-19 EP disclosed
US-5232940-A Controlling insects, plant nematodes, helminths, protozoa BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) 1993-08-03 US disclosed
US-5001262-A Method for synthesizing an aromatic hydrazine compound EASTMAN KODAK COMPANY (US) 1991-03-19 US disclosed
EP-0353931-A2 Method of making aromatic hydrazines EASTMAN KODAK COMPANY (US) 1990-02-07 EP disclosed
EP-0234119-A1 Pesticidal method using N-phenylpyrazoles RHONE-POULENC AGROCHIMIE (FR) 1987-09-02 EP disclosed
CN-86108643-A Insecticidal method using N-phenylpyrazoles 1987-07-29 CN disclosed
WO-1987003781-A1 PESTICIDAL METHOD USING N-PHENYLPYRAZOLES MAY & BAKER LIMITED (GB) 1987-07-02 WO disclosed