Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697631 | 0.76 | HMGCR (0.33) | — | |
| SCHEMBL5500130 | 0.75 | — | — | |
| SCHEMBL7554246 | 0.75 | USP2 (0.30) | — | |
| SCHEMBL18422774 | 0.69 | TSHR (0.36) | TSHR | |
| SCHEMBL10821764 | 0.69 | — | — | |
| SCHEMBL1117071 | 0.69 | TSHR (0.41) | TSHR | |
| SCHEMBL697418 | 0.68 | — | — | |
| SCHEMBL690606 | 0.68 | TSHR (0.34) | TSHR | |
| SCHEMBL7064860 | 0.68 | TSHR (0.34) | TSHR | |
| SCHEMBL11360771 | 0.67 | TSHR (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372883-B1 | FOR THERAPY AND PROPHYLAXIS OF INFECTIONS CAUSED BY HEPATITIS C, HEPATITIS G AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2002-04-16 | — | — | US | disclosed |