Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713710 | 1.00 | HIF1A (0.42) | HIF1ARAB9AGAASMN1; SMN2CYP1A2 | |
| SCHEMBL17937978 | 1.00 | HIF1A (0.42) | HIF1ARAB9AGAASMN1; SMN2CYP1A2 | |
| SCHEMBL828435 | 0.91 | HIF1A (0.47) | HIF1ARAB9ALMNAPTGS2NPC1 | |
| SCHEMBL13148668 | 0.91 | HIF1A (0.47) | HIF1ARAB9ALMNAPTGS2NPC1 | |
| SCHEMBL828434 | 0.91 | HIF1A (0.47) | HIF1ARAB9ALMNAPTGS2NPC1 | |
| SCHEMBL17937974 | 0.91 | HIF1A (0.47) | HIF1ARAB9ALMNAPTGS2NPC1 | |
| SCHEMBL7171770 | 0.91 | HIF1A (0.43) | HIF1ARAB9AKDM4ELMNAPTGS2 | |
| SCHEMBL7171768 | 0.91 | HIF1A (0.43) | HIF1ARAB9AKDM4ELMNAPTGS2 | |
| SCHEMBL7716053 | 0.90 | HIF1A (0.48) | HIF1ARAB9ASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL7716055 | 0.90 | HIF1A (0.48) | HIF1ARAB9ASMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | claimed |
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |