Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.59 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | TGM2 | P21980 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887546 | 1.00 | TDP1 (0.65) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL31672311 | 0.98 | TDP1 (0.62) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL15575825 | 0.95 | TDP1 (0.57) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL12318662 | 0.91 | TDP1 (0.51) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL721129 | 0.91 | TDP1 (0.55) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL2025761 | 0.88 | TDP1 (0.50) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL20841213 | 0.86 | TDP1 (0.49) | TDP1ZDHHC20ZDHHC2MAOAMAOB | |
| SCHEMBL134329 | 0.86 | TDP1 (0.85) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL3025184 | 0.86 | TDP1 (0.85) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL136815 | 0.86 | TDP1 (0.85) | TDP1MAOAMAOBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348322-B1 | DETECTION OF BINDING COMPOUNDS TO PROBES; PROVIDE TEST COMPOUND, INCUBATE WITH SUBSTRATE, ILLUMINATE, DETECT TRANSFER OF ENERGY, THE TRANSFER OF ENERGY INDICATES BINDING ACTIVITY | DUKE UNIVERSITY | 2002-02-19 | — | — | US | disclosed |