Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 4/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714158 | 1.00 | ELANE (0.37) | ELANEITGB1ITGA4GAAPARP1 | |
| SCHEMBL7265026 | 0.93 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7265032 | 0.93 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7265036 | 0.93 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7265041 | 0.93 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7718428 | 0.90 | ITGB1 (0.37) | ELANEITGB1ITGA4GAAPARP1 | |
| SCHEMBL7718420 | 0.90 | ITGB1 (0.37) | ELANEITGB1ITGA4GAAPARP1 | |
| SCHEMBL7716475 | 0.89 | ELANE (0.36) | ELANEITGB1ITGA4GAAPARP1 | |
| SCHEMBL7716472 | 0.89 | ELANE (0.36) | ELANEITGB1ITGA4GAAPARP1 | |
| SCHEMBL7714195 | 0.88 | ITGB1 (0.46) | ELANEITGB1ITGA4PARP1PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |