Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20545885 | 0.87 | CD274 (0.47) | KMT2ABCAT2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20545887 | 0.87 | CD274 (0.47) | KMT2ABCAT2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20546385 | 0.85 | CTSA (0.41) | KMT2ABCAT2CASP1SMN1; SMN2CTSA | |
| SCHEMBL20546383 | 0.85 | CTSA (0.41) | KMT2ABCAT2CASP1SMN1; SMN2CTSA | |
| SCHEMBL11397704 | 0.80 | KMT2A (0.44) | KMT2ABCAT2CASP1GABBR2GABBR1 | |
| SCHEMBL11487567 | 0.79 | PTGER1 (0.53) | KMT2ACASP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL2320843 | 0.78 | CTSA (0.47) | GABBR2GABBR1CTSA | |
| SCHEMBL5720952 | 0.78 | CTSA (0.47) | GABBR2GABBR1CTSA | |
| SCHEMBL31757740 | 0.78 | AKR1B1 (0.44) | KMT2AGABBR2GABBR1CYP1A2TSHR | |
| SCHEMBL5597477 | 0.78 | AKR1B1 (0.44) | KMT2AGABBR2GABBR1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432923-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | NOVARTIS AG (CH) | 2002-08-13 | — | — | US | disclosed |