Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628879 | 0.94 | MAPT (0.42) | PPARDLPAR3LPAR1LPAR2CES2 | |
| SCHEMBL4942146 | 0.93 | MAPT (0.46) | PPARDLPAR3LPAR1LPAR2CES2 | |
| SCHEMBL3929518 | 0.78 | PPARD (0.41) | PPARDCA1FNTAFNTBPGGT1B | |
| SCHEMBL3928093 | 0.78 | PPARD (0.41) | PPARDCA1FNTAFNTBPGGT1B | |
| Ethyl Hydrogen Butylphosphonate SCHEMBL575146 | 0.77 | PPARD (0.64) | PPARDLPAR3LPAR1LPAR2CETP | |
| SCHEMBL3005295 | 0.77 | CA1 (0.46) | CA1LPAR3LPAR2CES2CES1 | |
| SCHEMBL7616579 | 0.77 | KMT2A (0.44) | PPARDCES2CES1ALDH1A1 | |
| SCHEMBL8581475 | 0.77 | MAPT (0.44) | PPARDCES2CES1ALDH1A1 | |
| SCHEMBL11875238 | 0.76 | TSHR (0.49) | LPAR3LPAR1LPAR2 | |
| SCHEMBL10431817 | 0.76 | KMT2A (0.47) | PPARDCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376480-B1 | TREATMENT OF IMMUNE SYSTEM DISORDERS, OSTEOPOROSIS, ALOPECIA | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-23 | — | — | US | disclosed |
| US-6372731-B1 | TREATMENT OF CELL PROLIFERATION AND BONE DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-16 | — | — | US | disclosed |