Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708939 | 1.00 | ADRB3 (0.55) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7716909 | 0.85 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714674 | 0.85 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7712901 | 0.84 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714487 | 0.82 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714568 | 0.82 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714537 | 0.80 | ADRB3 (0.58) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7714864 | 0.80 | ADRB3 (0.58) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9271485 | 0.80 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9271478 | 0.80 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865421-B1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LTD (GB) | 2002-03-27 | — | — | EP | claimed |
| EP-0865421-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 1998-09-23 | — | — | EP | claimed |
| WO-1997021665-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 1997-06-19 | — | — | WO | claimed |
| EP-0865421-B1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LTD (GB) | 2002-03-27 | — | — | EP | disclosed |
| US-6048872-A | DIETETICS; ANTIDIABETIC AGENTS; CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO WELLCOME INC. (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0865421-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021665-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 1997-06-19 | — | — | WO | disclosed |