Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 9/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504032 | 0.94 | HTT (0.55) | RXRARXRBHTTALDH1A1NPC1 | |
| SCHEMBL10536373 | 0.93 | HAO1 (0.54) | RXRARXRBRARBHTTALDH1A1 | |
| SCHEMBL10527851 | 0.85 | RARB (0.53) | RXRARXRBRARBHTTALDH1A1 | |
| SCHEMBL10528505 | 0.82 | RARB (0.58) | RXRARXRBRARBALDH1A1MEN1 | |
| SCHEMBL10527437 | 0.81 | RARB (0.59) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL9793575 | 0.81 | SLC6A4 (0.50) | NPC1RAB9A | |
| SCHEMBL10529851 | 0.80 | RARB (0.61) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL10528096 | 0.80 | RARB (0.61) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL10536522 | 0.80 | RARB (0.61) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL10527690 | 0.80 | RARB (0.61) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376515-B2 | DERIVATIVES OF A 2-((4-AMIDINYLPHENYL)-CARBONYLAMINO-1,2-PHENYLENE)-CARBONYLAMINO-) PYRIDINE; POTENT AND HIGHLY SELECTIVE ANTICOAGULANTS; BIOAVAILABILITY AND/OR SOLUBILITY; PREVENTION AND TREATMENT OF THROMBOSIS AND COAGULATION | COR THERAPEUTICS, INC. | 2002-04-23 | — | — | US | disclosed |
| EP-0334925-A1 | FERROELECTRIC LIQUID CRYSTALLINE PHASES | MERCK PATENT GmbH (DE) | 1989-10-04 | — | — | EP | disclosed |