Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651765 | 0.81 | TLR4 (0.40) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2784766 | 0.81 | BRD4 (0.44) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13036801 | 0.80 | TLR4 (0.39) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL856267 | 0.80 | TLR4 (0.39) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3643881 | 0.80 | TLR4 (0.39) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL27868499 | 0.79 | BRD4 (0.42) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3579616 | 0.78 | BRD4 (0.44) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29134747 | 0.77 | BRD4 (0.36) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1650294 | 0.77 | BRD4 (0.50) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2670790 | 0.77 | BRD4 (0.50) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-4532081-A | 2-(6'-cyano-2'-hexynyl)-2-(b,b,b -trichlorocarboethoxy)-3-carbomethoxy cyclopentanone | THE DOW CHEMICAL COMPANY (US) | 1985-07-30 | — | — | US | disclosed |
| US-4447636-A | TRANS-2-B,B,B-TRICHLOROCARBOETHOXY-3 -CARBOMETHOXYCYCLOPENTANONE INTERMEDIATE | THE DOW CHEMICAL COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4146553-A | Intermediates for synthesizing 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4125556-A | Synthesis of 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1978-11-14 | — | — | US | disclosed |