SCHEMBL7715941

SCHEMBL7715941

CC(C)(C)COC(=O)CC(=O)OC1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.35
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
HTT P42858 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7718214 0.89
SCHEMBL7713893 0.82
SCHEMBL28733937 0.81 KDM4E (0.38) EPHX2KDM4ELMNAALDH1A1
SCHEMBL7715889 0.80 EPHX2 (0.34) EPHX2KDM4ELMNA
SCHEMBL7713917 0.80 EPHX2 (0.34) EPHX2KDM4ELMNAALDH1A1
SCHEMBL7710244 0.80 EPHX2 (0.34) EPHX2KDM4ELMNAALDH1A1
SCHEMBL32689094 0.79 EPHX2 (0.40) EPHX2KDM4ELMNAALDH1A1HPGD
SCHEMBL1087620 0.76 EPHX2 (0.41) EPHX2KDM4ELMNAALDH1A1
SCHEMBL7715401 0.74 KDM4E (0.32) EPHX2KDM4ELMNA
SCHEMBL2070936 0.74 EPHX2 (0.37) EPHX2KDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376632-B1 NORBORNENE COMPOUND CONTAINING CARBOXY GROUPS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-23 US claimed
US-6376632-B1 NORBORNENE COMPOUND CONTAINING CARBOXY GROUPS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-23 US disclosed