Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716156 | 1.00 | ITGB1 (0.39) | ITGB1ITGA4PDE10A | |
| SCHEMBL7716166 | 1.00 | ITGB1 (0.39) | ITGB1ITGA4PDE10A | |
| SCHEMBL7718440 | 0.92 | MAPT (0.34) | ITGB1ITGA4 | |
| SCHEMBL7718435 | 0.92 | MAPT (0.34) | ITGB1ITGA4 | |
| SCHEMBL7710720 | 0.91 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7710712 | 0.91 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7710717 | 0.91 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7718454 | 0.90 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7718447 | 0.90 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7718446 | 0.90 | ITGB1 (0.42) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | claimed |
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |