Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716443 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4PTGDRADORA2AKMT2A | |
| SCHEMBL7716453 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4PTGDRADORA2AKMT2A | |
| SCHEMBL7259164 | 0.88 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7259169 | 0.88 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7716463 | 0.88 | ITGB1 (0.39) | ITGB1ITGA4PTGDR | |
| SCHEMBL7716466 | 0.88 | ITGB1 (0.39) | ITGB1ITGA4PTGDR | |
| SCHEMBL7710707 | 0.88 | ITGB1 (0.39) | ITGB1ITGA4PTGDR | |
| SCHEMBL7264630 | 0.83 | ITGB1 (0.35) | ITGB1ITGA4 | |
| SCHEMBL7264633 | 0.83 | ITGB1 (0.35) | ITGB1ITGA4 | |
| SCHEMBL7265032 | 0.82 | ITGB1 (0.44) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |