Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | ALPI | P09923 | 1/20 | 0.65 |
| ▸ | ALPG | P10696 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571081 | 1.00 | MEN1 (0.79) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL2608363 | 0.88 | MEN1 (1.00) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL7538776 | 0.84 | MEN1 (0.74) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL2570389 | 0.84 | MEN1 (0.74) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL7538773 | 0.84 | MEN1 (0.74) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL2570390 | 0.84 | MEN1 (0.74) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL16199459 | 0.83 | KMT2A (0.88) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL2608357 | 0.83 | MEN1 (0.88) | MEN1KMT2AALDH1A1ALPIALPG | |
| SCHEMBL28969963 | 0.82 | NPC1 (0.64) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4940997 | 0.82 | GAA (0.64) | MEN1KMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395260-B1 | SKIN LIGHTENING COMPOSITIONS | HAARMANN & REIMER GMBH (DE) | 2002-05-28 | — | — | US | claimed |
| EP-1066821-A1 | Topical cosmetic product containing benzaldoxims | HAARMANN & REIMER GMBH (DE) | 2001-01-10 | — | — | EP | claimed |
| US-6395260-B1 | SKIN LIGHTENING COMPOSITIONS | HAARMANN & REIMER GMBH (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-1066821-A1 | Topical cosmetic product containing benzaldoxims | HAARMANN & REIMER GMBH (DE) | 2001-01-10 | — | — | EP | disclosed |
| US-3948861-A | Polyamide-imides from bis-imide and dialdoxime | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |