Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.50 |
| ▸ | FNTB | P49356 | 16/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717563 | 1.00 | FNTA (0.50) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7933897 | 0.84 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7716068 | 0.81 | FNTA (0.68) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7716070 | 0.81 | FNTA (0.68) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7718625 | 0.79 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7719418 | 0.79 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7714149 | 0.79 | FNTA (0.48) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7714146 | 0.79 | FNTA (0.48) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7717551 | 0.78 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7717552 | 0.78 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |