Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | ADK | P55263 | 1/20 | 0.57 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28346147 | 0.98 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL29160554 | 0.93 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| Oxalic Acid SCHEMBL31679098 | 0.90 | KDM4E (0.63) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL5803103 | 0.90 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL722191 | 0.83 | NISCH (0.78) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL30514712 | 0.82 | DYRK1A (0.47) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6055845 | 0.81 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL3407136 | 0.81 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL862114 | 0.81 | NISCH (0.75) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6630552 | 0.81 | SMPD3 (0.62) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206718-A | Core-shell material and preparation method thereof | 华为技术有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-117567509-A | Gold (I) gefitinib derivative and preparation method and application thereof | 华中科技大学同济医学院附属同济医院 | 2024-02-20 | — | — | CN | claimed |
| CN-108892681-A | A kind of imidazo [1,2-a] pyridines mercury ion Ratiometric fluorescent probe and its application | 泰山医学院 | 2018-11-27 | — | — | CN | claimed |
| CN-108218930-A | A kind of glycosyl diamine and its preparation method and application | 江南大学 | 2018-06-29 | — | — | CN | claimed |
| CN-103889964-B | Tumor targeting drug Combretastatin A4 derivative | NANJING SANHOME PHARMACEUTICAL CO.,LTD. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-101735217-B | Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug | UNIV GUANGDONG PHARM | 2012-09-26 | — | — | CN | claimed |
| CN-101735217-A | Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug | UNIV GUANGDONG PHARM | 2010-06-16 | — | — | CN | claimed |
| US-4411700-A | AMIDINE DERIVATIVES | FUJI PHOTO FILM CO., LTD. (JP) | 1983-10-25 | — | — | US | claimed |
| US-20250188072-A1 | COMPOUNDS FOR TREATMENT OF CANCER | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2025-06-12 | — | — | US | disclosed |
| US-12187720-B2 | Compounds for treatment of cancer | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2025-01-07 | — | — | US | disclosed |
| CN-118206718-A | Core-shell material and preparation method thereof | 华为技术有限公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2024081967-A2 | BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION | ZestBio, Inc. (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-117567509-A | Gold (I) gefitinib derivative and preparation method and application thereof | 华中科技大学同济医学院附属同济医院 | 2024-02-20 | — | — | CN | disclosed |
| CN-116970965-A | Electrochemical incomplete hydrogenation method of imidazopyridine compound | 上海兆维科技发展有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-4533550-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1985-08-06 | — | — | US | disclosed |
| EP-0006712-B1 | HETEROCYCLIC DERIVATIVES OF (4-ARYLOXYMETHYL-1.3-DIOXOLAN-2-YL) METHYL-1H-IMIDAZOLES AND -1H-1.2.4-TRIAZOLES, THEIR PREPARATION AND THE DERIVATIVES FOR USE AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-11-30 | — | — | EP | disclosed |
| US-4411700-A | AMIDINE DERIVATIVES | FUJI PHOTO FILM CO., LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| US-4313953-A | BACTERICIDES, FUNGICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-02-02 | — | — | US | disclosed |
| US-4218458-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-08-19 | — | — | US | disclosed |
| EP-0006712-A1 | Heterocyclic derivatives of (4-aryloxymethyl-1.3-dioxolan-2-yl) methyl-1H-imidazoles and -1H-1.2.4-triazoles, their preparation and the derivatives for use as fungicides and bactericides | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187720-B2 | Compounds for treatment of cancer | KLK3, BRDT, ACP3 | CYP1A2 4356/4885CYP3A4 4225/4885CYP2D6 3653/4885 |
| US-20250188072-A1 | COMPOUNDS FOR TREATMENT OF CANCER | KLK3, BRDT, ACP3 | CYP1A2 4356/4885CYP3A4 4225/4885CYP2D6 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.