Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166395 | 0.86 | TP53 (0.47) | MEN1KMT2ATP53NPC1EGFR | |
| SCHEMBL19114836 | 0.82 | TP53 (0.51) | MEN1KMT2AMAPTTP53NPC1 | |
| Laquinimod SCHEMBL39440 | 0.81 | TP53 (0.50) | MEN1KMT2ATP53NPC1RAB9A | |
| Laquinimod SCHEMBL29438575 | 0.81 | TP53 (0.50) | MEN1KMT2ATP53NPC1RAB9A | |
| Laquinimod SCHEMBL1573702 | 0.80 | TP53 (0.49) | MEN1KMT2ATP53NPC1RAB9A | |
| Laquinimod SCHEMBL1573337 | 0.80 | TP53 (0.49) | MEN1KMT2ATP53NPC1RAB9A | |
| SCHEMBL19114839 | 0.80 | TP53 (0.49) | MEN1KMT2AGAAMAPTTP53 | |
| Laquinimod SCHEMBL1573704 | 0.80 | TP53 (0.49) | MEN1KMT2ATP53NPC1RAB9A | |
| Laquinimod SCHEMBL1573491 | 0.80 | TP53 (0.49) | MEN1KMT2ATP53NPC1RAB9A | |
| Laquinimod SCHEMBL1991182 | 0.79 | TP53 (0.48) | MEN1KMT2AGAATP53EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | disclosed |