SCHEMBL7718100

SCHEMBL7718100

C=CC(=O)OC(C=C)CN

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.38
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
FGFR4 P22455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28250296 0.83 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7194659 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL851931 0.78 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28407507 0.78 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9362685 0.78 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL18181679 0.78 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3284084 0.77 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6533592 0.76
SCHEMBL27995286 0.76
SCHEMBL3966436 0.75 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500523-B1 INK ABSORBENT SHEET WITH INORGANIC PIGMENT AND BINDER GLOSSY SIDE AND CATIONIC COMPOUND OR POLYMER IMPREGNATED REVERSE SIDE; POST CARDS; INK JET PRINTABILITY CANON KABUSHIKI KAISHA (JP) 2002-12-31 US disclosed
EP-0709219-B1 Recording paper, and image forming method employing the same CANON KK (JP) 2000-01-12 EP disclosed
US-5908728-A Recording paper, and image forming method employing the same CANON KABUSHIKI KAISHA (JP) 1999-06-01 US disclosed
EP-0709220-B1 Recording medium, and image forming method employing the same CANON KK (JP) 1999-02-10 EP disclosed
EP-0709219-A1 Recording paper, and image forming method employing the same CANON KABUSHIKI KAISHA (JP) 1996-05-01 EP disclosed
EP-0709220-A1 Recording medium, and image forming method employing the same CANON KABUSHIKI KAISHA (JP) 1996-05-01 EP disclosed