Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HCN1 | O60741 | 2/20 | 0.35 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717590 | 0.82 | KDM4E (0.37) | MAPTCRHBPCRHR2NPSR1L3MBTL1 | |
| SCHEMBL9811161 | 0.82 | MAPT (0.58) | MAPTCRHBPCRHR2NPSR1DHFR | |
| SCHEMBL7718722 | 0.79 | CYP1A2 (0.38) | TSHRCYP1A2CYP2D6L3MBTL1MAPK1 | |
| SCHEMBL4650637 | 0.77 | NPC1 (0.34) | MAPTTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL13752166 | 0.75 | MAPT (0.73) | MAPTCRHBPCRHR2NPSR1DHFR | |
| SCHEMBL7720109 | 0.72 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL7720132 | 0.72 | MAPT (0.43) | MAPTTSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL9381224 | 0.70 | MAPT (0.56) | MAPTCRHBPCRHR2NPSR1DHFR | |
| SCHEMBL6567347 | 0.69 | NR3C2 (0.57) | MAPTCRHBPCRHR2NPSR1DHFR | |
| SCHEMBL409370 | 0.69 | NR3C2 (0.57) | MAPTCRHBPCRHR2NPSR1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808015-A | RED FIBER REACTIVE, ACID DYES FOR CELLULOSE FIBERS, COTTON, WOOL, SILK, POLYAMIDES, POLYESTERS, POLYOLEFINS AND POLYACRYLONITRILE; COLORFASTNESS; BRIGHTNESS; TRIAZINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | claimed |
| US-5744589-A | FOR DYEING OR PRINTING SUBSTRATES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | claimed |
| EP-0159962-B1 | FIBRE-REACTIVE CHROMIUM OR COBALT COMPLEXES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | claimed |
| US-4678851-A | FIBER-RACTIVE | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | claimed |
| US-6376656-B1 | DISAZO DYES, TRIAZINE DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-23 | — | — | US | disclosed |
| US-6046311-A | Water-soluble fiber-reactive dyes, preparation thereof and use thereof | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2000-04-04 | — | — | US | disclosed |
| US-6025478-A | HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS | BAYER AG (DE) | 2000-02-15 | — | — | US | disclosed |
| US-5955615-A | COUPLERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5831039-A | Fiber reactive polyazo dyes containing two urea groups | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0872523-A2 | Fiber-reactive azo dyes, process for their preparation and the use thereof | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5808015-A | RED FIBER REACTIVE, ACID DYES FOR CELLULOSE FIBERS, COTTON, WOOL, SILK, POLYAMIDES, POLYESTERS, POLYOLEFINS AND POLYACRYLONITRILE; COLORFASTNESS; BRIGHTNESS; TRIAZINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5760193-A | FOR COTTON, WOOL, POLYAMIDES; HIGH COLOR STRENGTH, COLORFASTNESS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-06-02 | — | — | US | disclosed |
| US-5274083-A | A 2-halopyrimidinylaminoalkylamino-4-chloro-6-sulfonyl-substituted chromophore group-s-triazine | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| US-5270454-A | Reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |
| WO-1993018224-A1 | PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES | CIBA-GEIGY AG (CH) | 1993-09-16 | — | — | WO | disclosed |
| US-5095102-A | 6-SUBSTITUTED SULPHONYL-8-SULPHO-2-NAPHTHYL MONOAZO REACTIVE DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5057609-A | TRIPHENDIOXAZINE DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| EP-0286021-B1 | REACTIVE AZO DYES | BASF Aktiengesellschaft (DE) | 1991-06-26 | — | — | EP | disclosed |
| US-4897469-A | Aniline series azo reactive dyes ortho- or para-substituted by vinyl sulfonyl reactive groups | BASF AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| EP-0286021-A2 | Reactive azo dyes | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |