SCHEMBL7718189

SCHEMBL7718189

C=C(C)C(=O)OCCCCC(C)O[SiH3]

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
THRB P10828 1/20 0.43
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 2/20 0.34
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3363130 0.95 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1898441 0.85 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3503120 0.83 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31636159 0.83 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL870590 0.83 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31636173 0.83 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31636152 0.83 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL382201 0.82 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19991477 0.81 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20503431 0.81 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110871269-B Alloy powder composition 大同特殊钢株式会社 2022-11-08 CN disclosed
CN-110871269-A Alloy powder composition 大同特殊钢株式会社 2020-03-10 CN disclosed
US-20020024011-A1 Method for correcting opaque defects in reticles for charged-particle-beam microlithography, and reticles produced using same NIKON CORPORATION 2002-02-28 US disclosed