Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757834 | 0.82 | KDM4E (0.52) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL30161776 | 0.82 | KDM4E (0.56) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL56776 | 0.82 | KDM4E (0.56) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL29466690 | 0.82 | KDM4E (0.56) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL5463849 | 0.81 | KDM4E (0.50) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL30423262 | 0.81 | KDM4E (0.50) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL28408631 | 0.81 | KDM4E (0.50) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL4926391 | 0.81 | KDM4E (0.50) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL16820308 | 0.80 | KDM4E (0.54) | KDM1AKDM4ELMNACCR1CCR5 | |
| SCHEMBL20591288 | 0.80 | KDM4E (0.54) | KDM1AKDM4ELMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6383986-B1 | USE AS HERBICIDES, DESICCANTS OR DEFOLIANTS AND PLANT SAFENING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-07 | — | — | US | disclosed |
| US-4297363-A | 2-Amino-3(4 or 5)-(pyridinyl)phenols and their use as cardiotonics | STERLING DRUG INC. (US) | 1981-10-27 | — | — | US | disclosed |