Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.66 |
| ▸ | FNTB | P49356 | 19/20 | 0.66 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718963 | 1.00 | FNTA (0.66) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7935969 | 0.95 | FNTA (0.63) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7721344 | 0.89 | FNTA (0.58) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7936718 | 0.88 | FNTA (0.65) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7933796 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7721347 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7933799 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7721355 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7714061 | 0.83 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7714063 | 0.83 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |