Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371307 | 0.83 | ABL1 (0.70) | ABL1ALOX5PTGS1PTGS2NOTUM | |
| SCHEMBL907934 | 0.82 | ABL1 (0.64) | ABL1ALOX5PTGS1PTGS2ADRB1 | |
| SCHEMBL908024 | 0.81 | ABL1 (0.67) | ABL1ALOX5PTGS1PTGS2ADRB1 | |
| SCHEMBL11376464 | 0.77 | ABL1 (0.53) | ABL1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL1357063 | 0.77 | ABL1 (1.00) | ABL1ALOX5PTGS1PTGS2ADRB1 | |
| SCHEMBL11380671 | 0.76 | ABL1 (0.51) | ABL1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL7719898 | 0.75 | ABL1 (0.79) | ABL1ALOX5PTGS1PTGS2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11089748 | 0.75 | ABL1 (0.97) | ABL1ALOX5PTGS1PTGS2ADRB1 | |
| SCHEMBL7719911 | 0.74 | ABL1 (0.77) | ABL1ALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL2268832 | 0.72 | ABL1 (0.61) | ABL1ALOX5PTGS1PTGS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387136-B1 | OXIDATION COLOR DYES AND COUPLER | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | claimed |
| EP-0974337-B1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | OREAL (FR) | 2001-03-21 | — | — | EP | claimed |
| EP-0974337-A1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | L'OREAL (FR) | 2000-01-26 | — | — | EP | claimed |
| US-4451479-A | ANTIINFLAMMATORY | AMERICAN CYANAMID COMPANY (US) | 1984-05-29 | — | — | US | claimed |
| EP-0022578-A1 | Pharmaceutical compositions containing 3-Amino-pyrazoline derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-21 | — | — | EP | claimed |
| US-6387136-B1 | OXIDATION COLOR DYES AND COUPLER | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | disclosed |
| EP-0974337-B1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | OREAL (FR) | 2001-03-21 | — | — | EP | disclosed |
| EP-0974337-A1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | L'OREAL (FR) | 2000-01-26 | — | — | EP | disclosed |
| US-4556671-A | Pharmaceutical formulations | BURROUGHS WELLCOME CO. (US) | 1985-12-03 | — | — | US | disclosed |
| US-4451479-A | ANTIINFLAMMATORY | AMERICAN CYANAMID COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
| US-4268436-A | OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |
| EP-0022578-A1 | Pharmaceutical compositions containing 3-Amino-pyrazoline derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-21 | — | — | EP | disclosed |