SCHEMBL7719447

SCHEMBL7719447

Fc1ccc(C[B-](Cc2ccc(F)cc2)(Cc2ccc(F)cc2)Cc2ccc(F)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
TAAR1 Q96RJ0 3/20 0.46
AGXT P21549 2/20 0.44
MAOB P27338 2/20 0.39
PLA2G1B P04054 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
MIF P14174 1/20 0.39
LMNA P02545 1/20 0.39
MAOA P21397 1/20 0.38
AOC3 Q16853 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19260349 0.80 IDO1 (0.48) IDO1LOXL2TAAR1AGXTMAOB
Potassium Ion SCHEMBL19260323 0.78 IDO1 (0.46) IDO1LOXL2TAAR1AGXTMAOB
SCHEMBL7437052 0.71 TAAR1 (0.68) IDO1LOXL2TAAR1AGXTMAOB
SCHEMBL1468357 0.71 IDO1 (0.58) IDO1LOXL2TAAR1AGXTMAOB
SCHEMBL16561361 0.71 IDO1 (0.58) IDO1LOXL2TAAR1AGXTMAOB
SCHEMBL8521849 0.71 PLA2G1B (0.40) IDO1LOXL2TAAR1AGXTMAOB
SCHEMBL7718327 0.71 IDO1 (0.44) IDO1TAAR1
SCHEMBL9508010 0.71 IDO1 (0.50) IDO1LOXL2TAAR1AGXTMAOB
SCHEMBL7719354 0.70 TAAR1 (0.52) IDO1TAAR1MAOBMIF
SCHEMBL5186843 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6387975-B1 ORGANOMETALLIC COMPOUND COMPLEX AUTEX, INC. (JP) 2002-05-14 US claimed
US-6387975-B1 ORGANOMETALLIC COMPOUND COMPLEX AUTEX, INC. (JP) 2002-05-14 US disclosed