Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.74 |
| ▸ | CTSD | P07339 | 11/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427973 | 0.85 | BACE1 (1.00) | BACE1CTSDKCNH2 | |
| SCHEMBL427974 | 0.85 | BACE1 (1.00) | BACE1CTSDKCNH2 | |
| SCHEMBL430504 | 0.85 | BACE1 (1.00) | BACE1CTSDKCNH2 | |
| SCHEMBL429086 | 0.85 | BACE1 (1.00) | BACE1CTSDKCNH2 | |
| SCHEMBL427982 | 0.85 | BACE1 (1.00) | BACE1CTSDKCNH2 | |
| SCHEMBL430760 | 0.84 | BACE1 (0.74) | BACE1CTSDKCNH2 | |
| SCHEMBL448739 | 0.83 | BACE1 (0.73) | BACE1CTSDKCNH2 | |
| SCHEMBL430500 | 0.77 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL429076 | 0.75 | BACE1 (0.77) | BACE1CTSDKCNH2 | |
| SCHEMBL431081 | 0.75 | BACE1 (0.77) | BACE1CTSDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |