Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306119 | 0.83 | EPHX2 (0.49) | — | |
| SCHEMBL1445939 | 0.79 | PRSS1 (0.48) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL4720670 | 0.77 | KMT2A (0.56) | — | |
| SCHEMBL48986 | 0.75 | PRSS1 (0.57) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL10211024 | 0.75 | PRSS1 (0.57) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL1446320 | 0.75 | PRSS1 (0.57) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL2198992 | 0.74 | PRSS1 (0.52) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL5221613 | 0.74 | ESR1 (0.44) | — | |
| SCHEMBL43650 | 0.74 | GFER (0.44) | LOXL2 | |
| SCHEMBL7428912 | 0.73 | PRSS1 (0.50) | PRSS1PRSS2PRSS3F10LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395737-B1 | ANTICOAGULANTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-05-28 | — | — | US | disclosed |