Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429224 | 0.85 | BACE1 (0.66) | BACE1 | |
| SCHEMBL430394 | 0.82 | BACE1 (0.75) | BACE1 | |
| SCHEMBL430471 | 0.82 | BACE1 (0.60) | BACE1 | |
| SCHEMBL7717661 | 0.82 | BACE1 (0.50) | BACE1 | |
| SCHEMBL430393 | 0.80 | BACE1 (0.60) | BACE1 | |
| SCHEMBL431057 | 0.78 | BACE1 (0.69) | BACE1 | |
| SCHEMBL428996 | 0.77 | BACE1 (0.67) | BACE1 | |
| SCHEMBL431033 | 0.76 | BACE1 (0.66) | BACE1 | |
| SCHEMBL429255 | 0.74 | BACE1 (0.57) | BACE1 | |
| SCHEMBL7893443 | 0.72 | BACE1 (0.90) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |