Styrene

Styrene

SCHEMBL7720508

C=CC#N.C=CC(=O)OCC(CC)CCCC.C=Cc1ccccc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.63
ALDH1A1 P00352 6/20 0.54
LMNA P02545 3/20 0.54
MAPK1 P28482 3/20 0.54
CYP3A4 P08684 3/20 0.50
CA2 P00918 1/20 0.50
TDP1 Q9NUW8 2/20 0.47
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
HSD17B10 Q99714 1/20 0.41
ATM Q13315 1/20 0.40
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
RECQL P46063 1/20 0.36
THRB P10828 2/20 0.35
THRA P10827 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL491218 0.93 TSHR (0.72) TSHRALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL1092186 0.89 TSHR (0.66) TSHRALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL9311792 0.89 TSHR (0.66) TSHRALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL27467831 0.88 TSHR (0.64) TSHRALDH1A1LMNAMAPK1CYP3A4
SCHEMBL8656083 0.87 TSHR (0.78) TSHRALDH1A1LMNAMAPK1CYP3A4
Acrylonitrile SCHEMBL7720260 0.87 TSHR (0.83) TSHRALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL6343509 0.87 TSHR (0.63) TSHRALDH1A1LMNAMAPK1CYP3A4
Acrylic Acid SCHEMBL7187166 0.86 TSHR (0.76) TSHRALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL8571224 0.85 TSHR (0.60) TSHRALDH1A1LMNAMAPK1CYP3A4
Styrene SCHEMBL29157682 0.85 TSHR (0.60) TSHRALDH1A1LMNAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6390538-B1 Impact absorbing member for vehicle interior KANEKA CORPORATION (JP) 2002-05-21 US disclosed