Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016025 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL9521214 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL7163178 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL15201698 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL15963880 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL6015980 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL8668910 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL9521223 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL9563973 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG | |
| SCHEMBL12427214 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152718-A1 | SACCHARIDE CONJUGATES | ARIZONA BOARD OF REGENTS, FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-0590348-B1 | Central venous catheters loaded with lipodalbaheptide antibiotics preventing development of catheter related infections | AVENTIS BULK S P A (IT) | 2002-02-27 | — | — | EP | disclosed |
| EP-0912604-B1 | Improved chemical process for preparing amide derivatives of antibiotic A 40926 | BIOSEARCH ITALIA SPA (IT) | 2001-11-14 | — | — | EP | disclosed |
| US-6218505-B1 | AMIDATION STEP IS CARRIED OUT IN THE PRESENCE OF A CONDENSING AGENT, AND PH IS CONTROLLED TO IMPROVE YIELDS; CHROMATOGRAPHIC PURIFICATION USING POLYAMIDE RESIN WHEREIN ONLY AQUEOUS SOLUTIONS ARE EMPLOYED FOR WASHINGS AND ELUTION | BIOSEARCH ITALIA S.P.A. (IT) | 2001-04-17 | — | — | US | disclosed |
| EP-0912604-A1 | IMPROVED CHEMICAL PROCESS FOR PREPARING AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | Biosearch Italia S.p.A. (IT) | 1999-05-06 | — | — | EP | disclosed |
| US-5750509-A | TREATMENT AGAINST INFECTIONS BY BACTERIA INCLUDING ENTEROCOCCUS, AND STAPHYLOCOCCUS | GRUPPO LEPETIT S.P.A. (IT) | 1998-05-12 | — | — | US | disclosed |
| WO-1997040067-A1 | IMPROVED CHEMICAL PROCESS FOR PREPARING AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | BIOSEARCH ITALIA S.P.A. (IT) | 1997-10-30 | — | — | WO | disclosed |
| US-5606036-A | BACTERICIDES | GRUPPO LEPETIT SPA (IT) | 1997-02-25 | — | — | US | disclosed |
| EP-0578644-B1 | ANTIBIOTIC A 40926 ESTER DERIVATIVES | LEPETIT SPA (IT) | 1996-12-04 | — | — | EP | disclosed |
| EP-0596929-B1 | AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | LEPETIT SPA (IT) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994021274-A1 | SYNERGISTIC COMBINATION OF ETHAMBUTOL AND A GLYCOPEPTIDE ANTIBIOTIC | GRUPPO LEPETIT S.P.A. (IT) | 1994-09-29 | — | — | WO | disclosed |
| CN-1088932-A | The amide derivative of antibiotic A 40926 | LEPETIT SPA (IT) | 1994-07-06 | — | — | CN | disclosed |
| EP-0590348-A1 | Central venous catheters loaded with lipodalbaheptide antibiotics preventing development of catheter related infections | GRUPPO LEPETIT S.p.A. (IT) | 1994-04-06 | — | — | EP | disclosed |
| EP-0578644-A1 | ANTIBIOTIC A 40926 ESTER DERIVATIVES. | LEPETIT SPA (IT) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017495-A1 | ANTIBIOTIC A 40926 ESTER DERIVATIVES | GRUPPO LEPETIT S.P.A. (IT) | 1992-10-15 | — | — | WO | disclosed |
| EP-0505735-A1 | Antibiotic A 40926 ester derivatives | GRUPPO LEPETIT S.p.A. (IT) | 1992-09-30 | — | — | EP | disclosed |