Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.86 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | HMGCR | P04035 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445407 | 0.94 | GCGR (0.78) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6953288 | 0.93 | GCGR (1.00) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6747779 | 0.91 | GCGR (0.74) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6871563 | 0.91 | GCGR (0.74) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL18947969 | 0.88 | GCGR (0.70) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL18947967 | 0.88 | GCGR (0.70) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL3407031 | 0.88 | GCGR (0.69) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL7077308 | 0.87 | GCGR (0.67) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL15029058 | 0.87 | GCGR (0.73) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL12074145 | 0.86 | GCGR (0.66) | GCGRESR1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6392050-B2 | REACTING 1,4-DIHYDROPYRIDINE WITH METHYL NITRITE IN PRESENCE OF ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | disclosed |