Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 16/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722217 | 0.91 | MCL1 (0.50) | MCL1UCHL1BCL2BCL2L1 | |
| SCHEMBL252870 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL9544995 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL6842708 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL192536 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL23452261 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL29015574 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL192535 | 0.90 | MCL1 (0.51) | MCL1UCHL1 | |
| SCHEMBL16369950 | 0.87 | MCL1 (0.42) | MCL1UCHL1 | |
| SCHEMBL16370849 | 0.87 | MCL1 (0.42) | MCL1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |