SCHEMBL7722877

SCHEMBL7722877

CCCCC[C@H]1CC[C@H](c2cc(F)c(C(F)(F)Oc3cc(F)c(F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722879 1.00 MEN1 (0.32) MEN1KMT2AGAAMAPT
SCHEMBL12626537 0.97 CYP2C9 (0.34) MEN1KMT2AGAAMAPT
SCHEMBL17552976 0.97 MEN1 (0.30) MEN1KMT2A
SCHEMBL7730842 0.96 CYP1A2 (0.30)
SCHEMBL7730846 0.96 CYP1A2 (0.30)
SCHEMBL12625827 0.94 MEN1 (0.31) MEN1KMT2AGAAMAPT
SCHEMBL16258079 0.94 MEN1 (0.31) MEN1KMT2AGAAMAPT
SCHEMBL7722484 0.93
SCHEMBL7722478 0.93
SCHEMBL7722479 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed