Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722949 | 1.00 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7731686 | 0.94 | PDE4D (0.33) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7731689 | 0.94 | PDE4D (0.33) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7733337 | 0.94 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7733335 | 0.94 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7733403 | 0.93 | PDE4D (0.33) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7733399 | 0.93 | PDE4D (0.33) | PDE4APDE4BPDE4CPDE4DFFAR1 | |
| SCHEMBL7730471 | 0.89 | FFAR4 (0.37) | FFAR4HCRTR1HCRTR2 | |
| SCHEMBL7730477 | 0.89 | FFAR4 (0.37) | FFAR4HCRTR1HCRTR2 | |
| SCHEMBL7729741 | 0.88 | MAOB (0.32) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |