Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430541 | 0.83 | BACE1 (0.62) | BACE1KCNH2 | |
| SCHEMBL430565 | 0.80 | BACE1 (0.61) | BACE1KCNH2 | |
| SCHEMBL428052 | 0.76 | BACE1 (0.64) | BACE1KCNH2 | |
| SCHEMBL430564 | 0.75 | BACE1 (0.62) | BACE1KCNH2 | |
| SCHEMBL14053739 | 0.68 | BACE1 (0.55) | BACE1 | |
| SCHEMBL14053740 | 0.68 | BACE1 (0.55) | BACE1 | |
| SCHEMBL15831390 | 0.67 | BACE1 (1.00) | BACE1KCNH2 | |
| SCHEMBL14053103 | 0.65 | BACE1 (0.59) | BACE1KCNH2 | |
| SCHEMBL14053104 | 0.65 | BACE1 (0.59) | BACE1KCNH2 | |
| SCHEMBL14053329 | 0.65 | BACE1 (0.46) | BACE1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |