Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.42 |
| ▸ | PPARA | Q07869 | 16/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727765 | 0.91 | KDM4E (0.47) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL7722471 | 0.84 | PPARG (0.41) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL7719068 | 0.84 | PPARG (0.43) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL7727703 | 0.84 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL1220163 | 0.82 | PPARG (0.45) | PPARGPPARAPPARDKDM4EFFAR1 | |
| SCHEMBL7723502 | 0.80 | PPARG (0.47) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL7724111 | 0.79 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL7722509 | 0.79 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL8877627 | 0.78 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL7727745 | 0.77 | PPARG (0.51) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700397-B1 | NEW THIAZOLIDINDIONES AND DRUGS CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 2002-09-04 | — | — | EP | claimed |
| US-5599826-A | ANTIDIABETIC AGENT | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-04 | — | — | US | claimed |
| US-5599826-A | ANTIDIABETIC AGENT | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-04 | — | — | US | disclosed |