Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732962 | 0.98 | TSHR (0.54) | TSHRKCNJ1KCNH2ALDH1A1EPHX1 | |
| SCHEMBL7733298 | 0.95 | TSHR (0.58) | TSHRKCNJ1KCNH2ALDH1A1LOXL2 | |
| SCHEMBL7733616 | 0.88 | TSHR (0.61) | TSHRKCNJ1KCNH2ALDH1A1LOXL2 | |
| SCHEMBL6821944 | 0.85 | TSHR (0.58) | TSHRKCNJ1KCNH2ALDH1A1EPHX1 | |
| SCHEMBL1527806 | 0.85 | MAPT (0.58) | TSHRKCNJ1KCNH2ALDH1A1HDAC1 | |
| SCHEMBL18913824 | 0.84 | TSHR (0.69) | TSHRKCNJ1KCNH2ALDH1A1LOXL2 | |
| SCHEMBL154515 | 0.83 | MAPT (0.61) | TSHRKCNJ1KCNH2ALDH1A1HDAC1 | |
| SCHEMBL7732578 | 0.83 | TSHR (0.56) | TSHRKCNJ1KCNH2ALDH1A1EPHX1 | |
| SCHEMBL1400171 | 0.83 | MAPT (0.61) | TSHRKCNJ1KCNH2ALDH1A1HDAC1 | |
| SCHEMBL2944805 | 0.83 | MAPT (0.61) | TSHRKCNJ1KCNH2ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |