Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.96 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.96 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.96 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.66 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL10796309 | 1.00 | ESR1 (0.96) | ESR1ESR2CYP19A1PTGS2PGR | |
| Phenol SCHEMBL10796314 | 1.00 | ESR1 (0.96) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL5354177 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL5354173 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL7723356 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL23851086 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL5818558 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL639225 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL13524705 | 0.91 | ESR1 (0.86) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL9451158 | 0.90 | ESR1 (0.83) | ESR1ESR2CYP19A1PTGS2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407083-B1 | ADMINISTERING AS 7-NITROBENZISOSELENAZOLINE DERIVATIVES AS ANTITUMOR AND ANTICARCINOGENIC AGENTS | OXIS INTERNATIONAL, INC. | 2002-06-18 | — | — | US | disclosed |
| US-6130212-A | ANTITUMOR | OXIS INTERNATIONAL S.A. (US) | 2000-10-10 | — | — | US | disclosed |
| US-6057310-A | TREATING LEUKEMIA, BREAST CANCER | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | disclosed |
| US-6001825-A | Use of novel organoselenium compounds as pro-oxidizing agents their methods of preparation and pharmaceutical compositions and application thereof | OXIS ISLE OF MAN, LIMITED (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0819682-A1 | Use of novel organoselenium compounds as pro-oxidizing agents, their methods of preparation and pharmaceutical compositions and application containing them | Oxis International S.A. (FR) | 1998-01-21 | — | — | EP | disclosed |