Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723603 | 1.00 | PARP1 (0.61) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL8559364 | 0.90 | PARP1 (0.55) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL20686435 | 0.88 | PARP1 (0.53) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| Hydrochloric Acid SCHEMBL11083764 | 0.87 | PARP1 (0.52) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| Dimethyl Maleate SCHEMBL7515581 | 0.85 | SMN1; SMN2 (0.49) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL2060236 | 0.83 | PARP1 (0.61) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL29922789 | 0.83 | PARP1 (0.61) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL29382709 | 0.82 | PARP1 (0.65) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL14406 | 0.82 | PARP1 (0.65) | PARP1SMN1; SMN2HDAC8HDAC6POLB | |
| SCHEMBL142937 | 0.82 | PARP1 (0.65) | PARP1SMN1; SMN2HDAC8HDAC6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399728-B1 | USING UNSATURATED DIESTER | ATOFINA CHEMICALS, INC. | 2002-06-04 | — | — | US | disclosed |